If a client has been premedicated for surgery with an opioid analgesic and the operative permit has not been signed, what action should the nurse take?

In the scenario where a client has been premedicated with an opioid analgesic and the operative permit has not been signed, notifying the surgeon that the consent form has not been signed is the appropriate action. It is crucial for the surgical team to verify that informed consent is obtained before any procedure is performed, especially since the client may currently have impaired judgment or altered mental status due to the effects of the medication. By notifying the surgeon, the nurse ensures that the surgical team is aware of the situation, allowing them to take the necessary steps to address it appropriately, which may include clarifying the client's ability to consent or delaying the procedure until proper consent can be obtained.

The other options do not adequately address the importance of obtaining valid consent in this situation. Reading the consent form to the client without confirming their ability to understand after medication does not fulfill the requirement for informed consent. Seeking the spouse's signature may not be appropriate if the client is still capable of understanding and making decisions. Administering an opioid antagonist is not justified in this context, as it may precipitate withdrawal symptoms or disrupt necessary pain management.